Figure 1 | Scientific Reports

Figure 1

From: Correlations between Gray Matter and White Matter Degeneration in Pure Alzheimer’s Disease, Pure Subcortical Vascular Dementia, and Mixed Dementia

Figure 1

TBSS in patients with PiB(+) ADD, PiB(−) SVaD, and PiB(+) SVaD compared to normal controls (NC). Warm color (red-yellow) indicates lower DTI indices in the dementia group compared to the NC group while cold color (blue-light blue) indicates higher DTI indices in the dementia group compared to the NC group. These results are overlaid on the MNI152 standard brain and the mean skeleton image (green color, FA > 0.2). Abbreviations: FWE, family-wise error; FA, fractional anisotropy; DR, radial diffusivity; DA, axial diffusivity; NC, normal controls; PiB, Pittsburgh compound B; ADD, Alzheimer’s disease dementia; SVaD, subcortical vascular dementia; TBSS, tract-based spatial statistics; DTI, diffusion tensor imaging; MNI, Montreal Neurological Institute.

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