Figure 1 | Scientific Reports

Figure 1

From: TGF-β participates choroid neovascularization through Smad2/3-VEGF/TNF-α signaling in mice with Laser-induced wet age-related macular degeneration

Figure 1

Morphological evaluation of mouse fundus at one week after Laser injury. The typical results of fundus photographs (A,B) and fundus fluorescein angiography (FFA, C,D) revealed that there were hyperfluorescence leakage in the Laser injured spots (white arrows) of fundus at one week after photocoagulation; the hematoxylin-eosin (HE) staining results (E,F, scale bar = 50 μm) showed that Laser-induced CNV presented vascular plexus with wide blood vessel lumen, which originated from the choroid and grew towards the bottom of the retina (black arrows) when compared with that of experimentally normal (Nor) control (sham treated).

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