Table 1 Blood and urinary glucose levels, daily water intake, body weights and relative kidney weights of the study groups.
Parameter | Co | Co-Cin | DM | DM-Cin | Pdiabetes | Ptreatment | Pinteraction |
---|---|---|---|---|---|---|---|
Blood glucose (mmol l−1) | 5.7 ± 0.4 | 6.1 ± 0.2 | 30.2 ± 1.6a,b | 30.3 ± 3.5a,b | <0.001 | 0.698 | 0.748 |
Daily water intake (ml day−1) | 33.4 ± 2.4 | 37.9 ± 2.6 | 239.8 ± 14.2a,b | 154.9 ± 15.7a,b,c | <0.001 | <0.001 | <0.001 |
Body weight (g) | 480 ± 60 | 478 ± 72 | 280 ± 27a,b | 254 ± 46a,b | <0.001 | 0.530 | 0.351 |
Kidney weight/body weight (mg g−1) | 2.5 ± 0.4 | 2.6 ± 0.3 | 5.6 ± 0.4a,b | 5.9 ± 0.6a,b | <0.001 | 0.265 | 0.305 |
Mean arterial blood pressure (mmHg) | 79.6 ± 6.8 | 80.1 ± 12.1 | 63.7 ± 8.5a,b | 64.4 ± 9.8a,b | <0.001 | 0.845 | 0.969 |