Figure 3 | Scientific Reports

Figure 3

From: Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu

Figure 3

Gene expression in H9c2 cells in response to H2O2-induced oxidative stress. (A) The majority of the differentially expressed (DE) genes were suppressed by H2O2 treatment, whereas YXS could recover the gene expression profile almost to the level of the control group. Yellow dots indicate differentially expressed genes, and blue dots represent genes with no significant difference. (B) Hierarchical clustering of differentially expressed genes in response to H2O2 treatment. (C and D) Over-represented GO terms for differentially expressed (DE) genes obtained from RNA-seq technology in the H2O2-induced model group compared with the control group (C) and in the cells pre-treated with YXS compared with the model group (D) by ClueGO.

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