Table 3 Association of ESRRG rs1890552 alleles with glucose, ba-PWV, and 8-epi-PGF in the NFG controls and subjects with IFG.

From: Influence of estrogen-related receptor γ (ESRRG) rs1890552 A > G polymorphism on changes in fasting glucose and arterial stiffness

 

Controls ( n = 374)

P

P’

IFG ( n = 155)

P

P’

A allele

G allele

A allele

G allele

Age (years)

44.8 ± 0.45

45.3 ± 0.50

0.481

 

49.5 ± 0.73

48.0 ± 0.67

0.125

 

BMI (kg/m2)

23.2 ± 0.14

23.2 ± 0.14

0.951

 

24.2 ± 0.25

24.0 ± 0.24

0.701

 

Change in weight (kg)

0.61 ± 0.14

0.62 ± 0.17

0.951

0.908

0.07 ± 0.25

0.21 ± 0.19

0.670

0.796

Glucose (mg/dL)

 Before

89.1 ± 0.30

89.6 ± 0.36

0.381

 

106.1 ± 0.50

105.9 ± 0.41

0.718

 

 After

90.6 ± 0.43††

90.7 ± 0.48

0.886

 

103.5 ± 1.33††

99.0 ± 1.01†††

0.004

 

 Change

1.50 ± 0.42

1.15 ± 0.51

0.594

0.862

−2.62 ± 1.18

−6.88 ± 0.91

0.004

0.005

ba-PWV (cm/s)

 Before

1269.3 ± 8.60

1275.2 ± 9.26

0.003

 

1315.1 ± 14.4

1378.5 ± 16.0

0.003

 

 After

1290.0 ± 9.81

1297.0 ± 9.94

0.528

 

1401.1 ± 17.3†††

1362.6 ± 19.2

0.387

 

 Change

20.7 ± 5.84

21.9 ± 6.58

0.056

0.884

860 ± 13.8

−15.9 ± 12.8

0.351

0.311

8-epi-PGF (pg/mg creatinine)

 Before

1325.6 ± 29.1

1447.6 ± 33.0

0.393

 

1405.5 ± 42.6

1580.1 ± 47.8

0.083

 

 After

1369.0 ± 28.1

1384.5 ± 29.8

0.429

 

1454.0 ± 52.2

1524.9 ± 51.8

0.135

 

 Change

57.3 ± 38.8

−52.3 ± 42.2

0.892

0.825

61.4 ± 71.6

−35.4 ± 74.4

<0.001

<0.001

  1. Means ± SE. Tested by logarithmic transformation. An independent t-test was used to calculate the P-values. The P’-values were adjusted for baseline values. P < 0.05, †† P < 0.01, and ††† P < 0.001 derived from paired t-tests before and after the follow-up period in each allele.