Table 3 Association of ESRRG rs1890552 alleles with glucose, ba-PWV, and 8-epi-PGF2α in the NFG controls and subjects with IFG.
Controls ( n = 374) | P | P’ | IFG ( n = 155) | P | P’ | |||
---|---|---|---|---|---|---|---|---|
A allele | G allele | A allele | G allele | |||||
Age (years) | 44.8 ± 0.45 | 45.3 ± 0.50 | 0.481 | 49.5 ± 0.73 | 48.0 ± 0.67 | 0.125 | ||
BMI (kg/m2) | 23.2 ± 0.14 | 23.2 ± 0.14 | 0.951 | 24.2 ± 0.25 | 24.0 ± 0.24 | 0.701 | ||
Change in weight (kg) | 0.61 ± 0.14 | 0.62 ± 0.17 | 0.951 | 0.908 | 0.07 ± 0.25 | 0.21 ± 0.19 | 0.670 | 0.796 |
Glucose (mg/dL)∮ | ||||||||
Before | 89.1 ± 0.30 | 89.6 ± 0.36 | 0.381 | 106.1 ± 0.50 | 105.9 ± 0.41 | 0.718 | ||
After | 90.6 ± 0.43†† | 90.7 ± 0.48 | 0.886 | 103.5 ± 1.33†† | 99.0 ± 1.01††† | 0.004 | ||
Change | 1.50 ± 0.42 | 1.15 ± 0.51 | 0.594 | 0.862 | −2.62 ± 1.18 | −6.88 ± 0.91 | 0.004 | 0.005 |
ba-PWV (cm/s)∮ | ||||||||
Before | 1269.3 ± 8.60 | 1275.2 ± 9.26 | 0.003 | 1315.1 ± 14.4 | 1378.5 ± 16.0 | 0.003 | ||
After | 1290.0 ± 9.81 | 1297.0 ± 9.94 | 0.528 | 1401.1 ± 17.3††† | 1362.6 ± 19.2 | 0.387 | ||
Change | 20.7 ± 5.84 | 21.9 ± 6.58 | 0.056 | 0.884 | 860 ± 13.8 | −15.9 ± 12.8 | 0.351 | 0.311 |
8-epi-PGF2α (pg/mg creatinine)∮ | ||||||||
Before | 1325.6 ± 29.1 | 1447.6 ± 33.0 | 0.393 | 1405.5 ± 42.6 | 1580.1 ± 47.8 | 0.083 | ||
After | 1369.0 ± 28.1† | 1384.5 ± 29.8 | 0.429 | 1454.0 ± 52.2 | 1524.9 ± 51.8 | 0.135 | ||
Change | 57.3 ± 38.8 | −52.3 ± 42.2 | 0.892 | 0.825 | 61.4 ± 71.6 | −35.4 ± 74.4 | <0.001 | <0.001 |