Figure 2

Expression of the PLCB1 gene after treatment with cocaine. (A) Expression levels in the nucleus accumbens of cocaine abusers compared with their matched controls. (B) Transcription levels in human dopaminergic neuron-like cells (differentiated SH-SY5Y) at different time points after a 30-min exposure to 5 μM cocaine. Significant differences compared to control cells (not exposed to cocaine) normalized to GAPDH are indicated. Error bars indicate s.d. *p-value < 0.05, **p-value < 0.01.