Figure 8 | Scientific Reports

Figure 8

From: Overexpression of C-type Natriuretic Peptide in Endothelial Cells Protects against Insulin Resistance and Inflammation during Diet-induced Obesity

Figure 8

Characteristics of OBEC mice, including pro-inflammatory cytokine expression in MesWAT. (a) Body weight over time. (b) Macroscopic appearance and (c) CNP mRNA levels in tissues of ob/ob and OBEC mice at 10 weeks of age. (d) Tissue weight ratio and (e) glucose tolerance testing in Wt and OBEC mice. (f) Expression of pro-inflammatory cytokines in MesWAT was determined by qPCR analysis. (g) Serum levels of pro-inflammatory cytokines was measured by ELISA. a.u., arbitrary units (copy number of gene of interest/copy number of reference gene [ribosomal protein 36B4]). n = 10 (a,c–g). *P < 0.05.

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