Table 1 Mean morphometric and metaphyseal bone structure data among lines at baseline (week 0, pooled by treatment), and mean diaphyseal cortical morphological indices at the end of the experiment (week 6). Data presented as means (SEM). Superscripts denote significant differences in means (pā<ā0.05) between a given group and: CLine C, LS1Line 1, LS2Line 2.
Ā | Line C | Line 1 | Line 2 |
---|---|---|---|
Morphometric Data | |||
Body mass (g) | 35.39 (1.07)LS1 | 39.57 (0.75)C,LS2 | 36.42 (0.81)LS1 |
Tibia length (mm) | 18.38 (0.14)LS1,LS2 | 21.26 (0.12)C | 21.17 (0.19)C |
Baseline Cortical Morphology ā Proximal Tibia | |||
TMD (mgHA/cm3) | 864.2 (10.8)LS1 | 810.97 (9.34)LS2,C | 860.2 (7.4)LS1 |
Ct.Th (mm) | 0.209 (0.003)LS1 | 0.171 (0.005)LS2,C | 0.209 (0.005)LS1 |
Ct.Ar (mm2) | 1.329 (0.028)LS1,LS2 | 1.167 (0.033)LS2,C | 1.456 (0.036)LS1,C |
Imax (mm4) | 0.619 (0.023)LS2 | 0.639 (0.041)LS2 | 0.807 (0.039)LS1,C |
Imin (mm4) | 0.482 (0.023)LS2 | 0.474 (0.03)LS2 | 0.618 (0.03)LS1,C |
J (mm4) | 1.101 (0.044)LS2 | 1.113 (0.072)LS2 | 1.425 (0.066)LS1,C |
Baseline Trabecular Morphology ā Proximal Tibia | |||
TV (mm3) | 2.039 (0.071)LS1,LS2 | 2.443 (0.130)C | 2.68 (0.087)C |
BV (mm3) | 0.785 (0.037)LS1,LS2 | 0.560 (0.047)C | 0.535 (0.038)C |
BV/TV (%) | 38.9 (2.1)LS1, LS2 | 23.2 (1.9)C | 20.2 (1.4)C |
Tb.N (1/mm) | 5.28 (0.25)LS1,LS2 | 4.15 (0.26)LS2, C | 2.42 (0.13)LS1,C |
Tb.Th (mm) | 0.085 (0.002)LS1,LS2 | 0.072 (0.001)C | 0.074 (0.001)C |
Tb.Sp (mm) | 0.186 (0.011)LS2 | 0.243 (0.020)LS2 | 0.454 (0.024)LS1,C |
6-week Postoperative Cortical Morphology ā Distal Tibia | |||
Ct.Ar (mm2) | 0.819 (0.023) | 0.861 (0.025) | 0.8 (0.025) |
Ct.Th (mm) | 0.231 (0.005) | 0.244 (0.008) | 0.234 (0.007) |
Canal Thickness (mm) | 0.019 (0.006) | 0.013 (0.002) | 0.012 (0.001) |
Porosity (%) | 0.605 (0.078) | 0.608 (0.101) | 0.514 (0.073) |
Zp (mm3) | 0.283 (0.015) | 0.293 (0.012) | 0.275 (0.012) |
Canal Longit Angle (°) | 33.8 (1.7)LS1 | 40.7 (1.7)LS2, C | 31.9 (1.3)LS1 |
Canal Radial Angle (°) | 40.8 (1.9) | 40.3 (1.6) | 40.6 (2.7) |