Table 1 Single channel conductance of PKD2L1 and mutants.

From: Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing

Slope conductance

Inward (-100~40 mV)

n

Outward (40~140 mV)

n

WT

161.9 ± 4.7 pS

15

102.4 ± 5.0 pS

16

K452Q

117.3 ± 5.5 pS

9

137.8 ± 9.6

7

K455Q

125.5 ± 6.2 pS

7

77.0 ± 3.0 pS

9

K461Q

184.3 ± 9.7 pS

10

85.9 ± 5.7 pS

15

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