Table 3 Half-maximal activated voltage and slope factor estimated from the voltage-clamp experiments in PKD2L1 for each channel type.

From: Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing

Type

V 0.5 (mV)

z/kBT

WT

138.3

0.0249

K452Q

295.0

0.0234

K455Q

280.0

0.0233

K461Q

182.7

0.0217