Table 1 Clinical characteristics of patients in the screening cohorta.

From: Polymorphisms in MICA, but not in DEPDC5, HCP5 or PNPLA3, are associated with chronic hepatitis C-related hepatocellular carcinoma

Parameter

HCC (n = 142)

Non-HCC (n = 575)

p-value

Age (years)

67 ± 9

59 ± 13

<0.0001

Sex (female/male)

42/100

326/249

<0.0001

HCV viral load (log copies/mL)

6.0 ± 1.0

6.2 ± 1.0

0.0718

CH/LC

54/88

487/88

<0.0001

AST (IU/L)

69 ± 41

49 ± 34

<0.0001

ALT (IU/L)

66 ± 43

55 ± 49

<0.0001

Platelets (×104/µL)

12.3 ± 6.1

16.7 ± 6.0

<0.0001

Albumin (g/dL)

3.8 ± 0.4

4.2 ± 1.8

<0.0001

PT%

88 ± 18

99 ± 16

<0.0001

AFP (ng/mL)

630 ± 4357

11 ± 24

<0.0001

PIVKA-II (mAU/mL)

2098 ± 9992

23 ± 43

<0.0001

IL28B rs8099917 (TT/TG/GG)b

96/34/1

391/143/12

0.5660

ITPA rs1127354 (CC/CA/AA)b

94/35/2

406/130/9

0.7309

  1. aContinuous variables are shown as the mean ± SD.
  2. b11 HCC and 30 non-HCC samples were lost to examine the IL28B and ITPA SNPs, respectively.
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