Table 2 Logistic regression analysis of independent factors related to HCC development

Age (≥66 years vs.<65 years)

3.68 (2.02–6.71)

<0.0001

Sex (male vs. female)

4.01 (2.21–7.27)

<0.0001

AST (≥40 IU/L vs. <40 IU/L)

1.04 (0.47–2.32)

0.9243

ALT (≥40 IU/L vs. <40 IU/L)

1.52 (0.71–3.23)

0.2797

Plt (≤15 × 10⁴/µL vs. >15 × 10⁴/µL)

1.26 (0.67–2.36)

0.4719

Alb (≤4 g/dL vs. >4 g/dL)

2.84 (1.49–5.42)

0.0015

PT% (≤70 vs. >70)

3.90 (1.32–11.56)

0.0140

AFP (≥20 ng/mL vs. <20 ng/mL)

4.31 (2.19–8.49)

<0.0001

PIVKA-II (≥40 mAU/mL vs. <40 mAU/mL)

11.44 (5.32–24.57)

<0.0001

MICA genotypes (minor vs. non-minor)

4.47 (2.04–9.80)

0.0002