Table 1 Echocardiography measurements in 15-epi-LXA4 treated and MI-control mice post-MI.

From: Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing

Parameters/groups

d0 naïve control

MI-day 1

MI-day 5

MI-control

Lipo-15-epi-LXA4

15-epi-LXA4

MI-control

Lipo-15-epi-LXA4

15-epi-LXA4

n

6

9

8

7

9

6

5

Heart rate (bpm)

433 ± 14

450 ± 9

464 ± 9

480 ± 13

440 ± 12

504 ± 20

485 ± 13

EDD (mm)

3.6 ± 0.1

4.8 ± 0.2*

4.4 ± 0.1*

4.3 ± 0.2 *

5.6 ± 0.1*

5.4 ± 0.4*

5.0 ± 0.3*#

ESD (mm)

2.4 ± 0.1

4.4 ± 0.1*

4.0 ± 0.1*#

3.9 ± 0 0.2*#

5.3 ± 0.1*

4.9 ± 0.5*#

4.6 ± 0.4*#

Fractional shortening %

35 ± 2

8 ± 1*

10 ± 1*

10 ± 1*

6 ± 1*

10 ± 2*#

8 ± 2*

PWTs (mm)

1.04 ± 0.05

0.54 ± 0.03*

0.59 ± 0.04*

0.57 ± 0.04*

0.54 ± 0.04*

0.58 ± 0.07*

0.52 ± 0.03*

IVSs (mm)

1.0 ± 0.02

0.65 ± 0.05*

0.63 ± 0.04*

0.62 ± 0.05*

0.55 ± 0.03*

0.74 ± 00.01*#

0.57 ± 0.09*

PWTd(mm)

0.65 ± 0.04

0.48 ± 0.04*

0.52 ± 0.04*

0.50 ± 0.04*

0.45 ± 0.03*

0.48 ± 0.05*

0.50 ± 0.02*

IVSd (mm)

0.71 ± 0.03

0.55 ± 0.03*

0.55 ± 0.03*

0.52 ± 0.03*

0.50 ± 0.03*

0.61 ± 0.02*#

0.50 ± 0.02*

  1. Values are mean ± SEM; n indicates sample size. bpm, beats per minute; EDD, end-diastolic dimension; ESD, end-systolic dimension; PWT, Posterior wall thickness; IVSs, Interventricular septal end systole; IVSd, interventricular septal end diastole; mm, millimeter; µl, microliter. *p < 0.05 vs. day 0 naïve control; # p < 0.05 vs. MI-control with respective time point.