Figure 8
From: High-fat diet increases pain behaviors in rats with or without obesity
High-fat diet increases macrophage density in the lumbar DRG. Sample micrographs of Iba-1 labelling in cross sections of DRG from rats fed a high-fat diet for 6 weeks (A, Long-Evans; D, Sprague-Dawley) or maintained on normal chow (B, Long-Evans; E, Sprague-Dawley). No pain model was implemented. Scale bar 100 µm. Summary data of normalized intensity is shown in C (Long-Evans) and F (Sprague-Dawley). N = 4 male Sprague-Dawley or 5 male Long-Evans rats per group, with 17–44 sections measured per animal. *p < 0.05; **p < 0.01; significantly different from high-fat group (Mann-Whitney test).
