Figure 1 | Scientific Reports

Figure 1

From: A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma

Figure 1

Forest plots showing association of IFNL polymorphisms and atopy in sub-groups based on age and gender in different cohorts. The tag-SNP rs12979860 was used in all other cohorts except the Polish cohort that tested for functional polymorphism rs368234815. A dominant model of inheritance for the minor allele (Ex. TT/ ΔG + ΔG/ ΔG vs TT/TT for rs368234815) was used in all cohorts except in the COPSAC cohort that used an additive model to obtain Odds Ratios (OR) shown as a forest plot. p-value < 0.05 was considered as significant and is in bold. For stratification based on age 50 yr was used as a cut-off mark. Het.-heterogeneity.

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