Figure 3 | Scientific Reports

Figure 3

From: A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma

Figure 3

Forest plots showing the summary estimates obtained from all the participants or from different groups based on age and gender after meta-analysis of data from different cohorts for (A) atopy and (B) asthma. The association was tested with atopy or asthma and rs12979860 using a dominant model for the minor allele (CT + TT vs CC) in all cohorts except for atopy in the COPSAC cohort where an additive model (for minor allele T) was used. The cohorts included in each of the meta-analysis and the effect heterogeneity between different cohorts is shown. p-value < 0.05 was considered as significant and is in bold. Meta-analysis was performed using a random-effects model, while the results were similar using the fixed-effects model too.  For stratification based on age 50 yr was used as a cut-off mark. Het.-heterogeneity.

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