Table 1 Characteristics of the study subjects in the Polish cohort.

From: A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma

 

asthma, N = 326

controls, N = 111

age, years*

59.2 ± 15.9 (18–94)

52.3 ± 18.3 (24–81)

gender, women, n (%)

201 (61.7%)

72 (64.9%)

Men > 50 yr average age (range)/n

67.3 ± 9.8 (50–87)/92

65.2 ± 9.7 (50–80)/18

Men < 50 yr average age (range)/n

34.2 ± 7.5 (18–48)/33

32.9 ± 5.9 (24–48)/21

Women > 50 yr average age (range)/n

67.3 ± 9.3 (50–94)/144

67 ± 7.2 (51–81)/47

Women < 50 yr average age (range)/n*

40 ± 6.6 (24–49)/57

34.1 ± 6.5 (26–49)/25

Atopy, n/N tested (%)*

141/273 (51.6%)

39/111 (35.1%)

FEV1% pred.

75.3 ± 24.1 (17.5–129.5)

FEV1%/FVC

68 ± 13.1 (25.6–99.4)

ACT, points

17.8 ± 5.5(4–25)

FeNO (ppb)

30.6 ± 17.8 (2–184)

Asthma control (according to GINA 2016)

  Controlled, n (%)

72 (22%)

  partly controlled, n (%)

96 (30%)

  Uncontrolled, n (%)

156 (48%)

Current asthma treatment

  ICS, n (%)

240 (73.6%)

  low dose**, n (%)

28 (8.6%)

 

  medium dose**, n (%)

120 (36.8%)

 

  high dose dose**, n (%)

92 (28.2%)

 

  Oral steroids, n (%)

23 (7.1%)

  LABA, n (%)

197 (60.4%)

 

  Leukotriene antagonists, n (%)

64 (19.6%)

 

  at least 1 exacerbation/last year, n (%)

170 (52.1%)

  1. Values are presented as arithmetic means + SD, (range); *statistically significant difference between groups, p < 0.05; values shown in bold; **according to GINA 2016.