Figure 5
From: Peripheral serotonin regulates postoperative intra-abdominal adhesion formation in mice
Deficiency of serotonin relieved the disorder of the fibrinolytic system in postoperative intra-abdominal adhesion formation in mice. Postoperative intra-abdominal adhesion formation was induced by caecum rubbing, and the mice were sacrificed on the 1st, 3rd and 7th days after the operation. The peritoneal fluids were harvested to evaluate the fibrinolytic system. The levels of (A) t-PA and (B) PAI-1 in the peritoneal fluids; (C) t-PA/PAI-1ratio in the peritoneal fluids; (D) The fibrinogen content in the peritoneal fluids; n = 6, mean ± SEM, *P < 0.05 vs. the WT group.
