Table 1 Demographic and clinical characteristics of study samples.
From: SIRT1 rs10823108 and FOXO1 rs17446614 responsible for genetic susceptibility to diabetic nephropathy
Characteristics | Case (n = 653) | Control (n = 413) | P | OR | |
|---|---|---|---|---|---|
Sociodemographic Factors | |||||
Gender | male | 413(63.25%) | 255(61.74%) | 1 | |
female | 240(36.75%) | 158(38.26%) | 0.62 | 0.94(0.73, 1.21) | |
Age (years) | 62.46 ± 11.04 | 58.35 ± 12.07 | < 0.01 | ||
Diabetes-related Variables | |||||
Duration of diabetes (years) | 11.54 ± 7.47 | 14.29 ± 4.95 | < 0.01 | ||
BMI (kg/m2) | 26.19 ± 2.55 | 25.25 ± 2.74 | < 0.01 | ||
HbA1C (%) | 8.88 ± 2.23 | 8.54 ± 1.74 | < 0.01 | ||
Lifestyle behaviors | |||||
Smoking | no | 483(73.97%) | 330(79.90%) | 1 | |
yes | 170(26.03%) | 83(20.10%) | 0.03 | 1.40(1.04, 1.88) | |
Drinking | no | 553(84.69%) | 361(87.41%) | ||
yes | 100(15.31%) | 52(12.59%) | 0.22 | 1.26(0.88, 1.80) | |
Biochemical variables | |||||
Total cholesterol (mmol/L) | 4.40 ± 1.39 | 4.23 ± 1.09 | 0.03 | ||
Triglycerides (mmol/L) | 1.87 ± 1.40 | 1.80 ± 1.80 | 0.47 | ||
HDL-C (mmol/L) | 1.06 ± 0.33 | 1.13 ± 0.35 | < 0.01 | ||
LDL-C (mmol/L) | 2.65 ± 1.00 | 2.55 ± 0.87 | 0.11 | ||
History of diseases | |||||
Hypertension | no | 231(35.38%) | 213(51.57%) | 1 | |
yes | 422(64.62%) | 200(48.43%) | < 0.01 | 1.95(1.51, 2.50) | |
DM Family history | no | 414(63.40%) | 259(62.71%) | 1 | |
yes | 239(36.60%) | 154(37.29%) | 0.82 | 0.97(0.75, 1.25) | |
