Table 4 Haplotype Analysis of five Polymorphism Sites.
From: SIRT1 rs10823108 and FOXO1 rs17446614 responsible for genetic susceptibility to diabetic nephropathy
Gene | Haplotype | Cases (%) | Controls (%) | χ2 | P | OR (95%CI) |
|---|---|---|---|---|---|---|
SIRT1a | A C A | 11.89(9.0) | 10.70(1.3) | 0.72 | 0.40 | 0.70(0.31, 1.61) |
A C G | 562.12(43.0) | 343.59(41.6) | 0.43 | 0.51 | 1.06(0.89, 1.27) | |
A T A | 29.55(2.3) | 26.76(3.2) | 1.88 | 0.17 | 0.69(0.41, 1.18) | |
A T G | 358.44(27.4) | 216.95(26.3) | 0.36 | 0.55 | 1.06(0.87, 1.29) | |
G C A | 4.44(0.3) | 5.31(0.6) | 1.02 | 0.31 | 0.53(0.15, 1.87) | |
G C G | 14.55(1.1) | 14.41(1.7) | 1.50 | 0.22 | 0.64(0.31, 1.32) | |
G T A | 293.12(22.4) | 187.23(22.7) | 0.01 | 0.90 | 0.99(0.80, 1.22) | |
G T G | 31.89(2.4) | 21.05(2.5) | 0.02 | 0.88 | 0.96(0.55, 1.67) | |
FOXO1b | A C | 209.39(16.0) | 93.44(11.3) | 9.25 | 0.00 | 1.50(1.15, 1.94) |
A T | 108.61(8.3) | 11.56(1.4) | 45.52 | 0.00 | 1.79(1.06, 2.80) | |
G C | 646.61(49.5) | 460.56(55.8) | 7.91 | 0.00 | 0.78(0.65,0.93) | |
G T | 341.39 (26.1) | 260.44(31.5) | 7.26 | 0.01 | 0.77(0.63,0.93) |
