Table 5 Combined Effect of the five SNPs on DN.
From: SIRT1 rs10823108 and FOXO1 rs17446614 responsible for genetic susceptibility to diabetic nephropathy
Combined SNPs | Cases (%) | Controls (%) | χ2 | P | OR (95%CI) |
---|---|---|---|---|---|
0–2 | 123(18.84) | 76(18.41) | 1 | ||
3–4 | 340(50.07) | 232(56.17) | 0.35 | 0.56 | 0.91(0.65, 1.26) |
5–6 | 170(26.03) | 96(23.24) | 0.22 | 0.64 | 1.09(0.75, 1.60) |
≥7 | 20(3.06) | 9(2.18) | 0.55 | 0.46 | 1.37(0.60, 3.17) |
0.81a | 0.37a | ||||
Total | 653 | 413 |