Figure 6 | Scientific Reports

Figure 6

From: New molecular insights into the tyrosyl-tRNA synthase inhibitors: CoMFA, CoMSIA analyses and molecular docking studies

Figure 6

CoMSIA contour maps with compound 15 as template. (a) Steric: Green contours favored bulky regions, and yellow contours bulkily disfavored regions. (b) Electrostatic: Red contours indicates electron-withdrawing groups favored, and blue contours means electron-donating groups favored. (c) H-bond acceptor: Magenta and red contours indicate h-bond acceptor favorable and unfavorable respectively. (d) H-bond donor: Cyan and purple contours stand for favorable and unfavorable respectively.

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