Table 1 Metal concentrations in the human olfactory bulb and tract in normal (n = 4) and Parkinson’s disease (PD; n = 4) patients. Values are mean ± SEM, wet weight. LoD: Limit of detection (3 σblank); LoQ: Limit of quantification (10 σblank).
From: Metal concentrations and distributions in the human olfactory bulb in Parkinson’s disease
Element | LoD (µg/g) | LoQ (µg/g) | Parkinson’s disease | Normal | ||
---|---|---|---|---|---|---|
Olfactory bulb (µg/g) | Olfactory tract (µg/g) | Olfactory bulb (µg/g) | Olfactory tract (µg/g) | |||
23Na Sodium | 0.0091 | 0.0302 | 2,770.74** ± 123.96 | 2,567.88** ± 66.99 | 1,768.34 ± 152.67 | 1496.32 ± 112.69 |
54Fe Iron | 0.0168 | 0.0560 | 24.27* ± 2.53 | 19.49 ± 2.51 | 16.70 ± 0.41 | 19.55 ± 1.69 |
63Cu Copper | 0.0001 | 0.0003 | 1.59 ± 0.119 | 1.01 ± 0.205 | 1.64 ± 0.168 | 1.29 ± 0.396 |
39K Potassium | 0.0060 | 0.0199 | 1,827.89 ± 271.60 | 1,851.38 ± 224.57 | 1,534.15 ± 141.87 | 2,031.56 ± 256.64 |
43Ca Calcium | 0.0342 | 0.1141 | 438.44 ± 102.34 | 476.03 ± 174.13 | 262.43 ± 140.54 | 227.87 ± 48.43 |
24Mg Magnesium | 0.0090 | 0.0301 | 74.58 ± 4.78 | 76.43 ± 3.84 | 60.78 ± 2.41 | 64.74 ± 3.65 |
68Zn Zinc | 0.0008 | 0.0027 | 19.04 ± 5.37 | 40.46 ± 10.60 | 31.92 ± 9.95 | 25.62 ± 7.56 |
85Rb Rubidium | 0.0000 | 0.0000 | 1.455 ± 0.100 | 1.686 ± 0.180 | 1.776 ± 0.202 | 2.301 ± 0.213 |
60Ni Nickel | 0.0001 | 0.0004 | 0.260 ± 0.102 | 0.900 ± 0.379 | 0.536 ± 0.201 | 0.351 ± 0.141 |
52Cr Chromium | 0.0003 | 0.0010 | 0.261 ± 0.020 | 0.331 ± 0.026 | 0.2 44 ± 0.023 | 0.249 ± 0.031 |
55Mn Manganese | 0.0001 | 0.0003 | 0.179 ± 0.013 | 0.185 ± 0.015 | 0.169 ± 0.007 | 0.147 ± 0.013 |
207Pb Lead | 0.0001 | 0.0003 | 0.062 ± 0.025 | 0.137 ± 0.053 | 0.096 ± 0.021 | 0.063 ± 0.033 |
51V Vanadium | 0.0001 | 0.0002 | 0.077 ± 0.005 | 0.096 ± 0.009 | 0.077 ± 0.008 | 0.070 ± 0.010 |