Table 1 Demographic variables and clinical characteristics of adolescent-onset and adult-onset antipsychotic-naïve, first-episode schizophrenia patients and healthy control subjects.
Characteristic | Adolescent participants | P | Adult participants | P | ||||
|---|---|---|---|---|---|---|---|---|
FES group | Healthy group | comparison | FES group | Healthy group | comparison | |||
(N = 26) | (N = 26) | t/χ 2 | (N = 49) | (N = 57) | t/χ 2 | |||
Age (years); mean (SD) | 16.87(1.05) | 16.81(0.75) | 0.12 | 0.22 | 32.88(5.94) | 32.88(6.26) | 0.03 | 0.86 |
Education (years); mean (SD) | 10.35(1.38) | 11.19(1.02) | 5.81 | 0.02 | 12.33(4.12) | 13.02(4.21) | 0.01 | 0.87 |
Sex (male: female) | 13:13 | 13:13 | 0 | 1 | 20:29 | 26:31 | 0.03 | 0.62 |
TMV; mean (SD) | 1,254.50 (137.15) | 1,262.87 (85.69) | −0.26 | 0.79 | 1,166.91 (105.73) | 1,214.48 (109.84) | −2.26 | 0.03 |
Illness duration (months); mean (SD) | 3.61(3.50) | 4.85(7.29) | ||||||
Age onset (years); mean (SD) | 16.51(1.01) | 32.48(5.83) | ||||||
Global assessment function; mean (SD) | 27.96(8.19) | 27.31(8.17) | ||||||
PANSS scores; mean (SD) | ||||||||
Total | 93.42(16.43) | 89.22(17.15) | ||||||
Negative | 20.46(8.19) | 16.7(6.38) | ||||||
Positive | 25.12(4.92) | 25.89(5.85) | ||||||
General | 47.85(9.88) | 46.63(9.89) | ||||||
Thought disturbance | 13.65(3.74) | 14.11(3.59) | ||||||
Activation | 9.12(2.86) | 9.43(3.77) | ||||||
Paranoid | 10.62(2.00) | 11.04(2.92) | ||||||
Impulsive aggression | 16.85(5.14) | 16.28(4.67) | ||||||
Anergia | 9.77(4.88) | 7.87(3.46) | ||||||
Depression | 9.15(3.94) | 8.74(4.16) | ||||||
