Figure 2 | Scientific Reports

Figure 2

From: PIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer

Figure 2

Disease-specific survival according to the PIK3CA mutation status in endometrial cancer. (a) PIK3CA mutation (exon9 and/or exon20) compared to no mutation detected. (b) PIK3CA exon9 mutations compared to PIK3CA exon20 mutations or non-mutated. (c) PIK3CA exon9 mutation leading to a change from negative to positive charge at affected amino acids (AA+), compared to mutation not leading to change of charge (AA°) and compared to no mutation. Curves are plotted by the Kaplan-Meier method; n = number of cases in each category followed by number of disease specific deaths, with comparison of survival between categories using log-rank (Mantel-Cox) test.

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