Table 1 Baseline characteristics of naïve and experienced users of osteoporotic medication after hip fracture.

From: Primary and secondary non-adherence to osteoporotic medications after hip fracture in Spain. The PREV2FO population-based retrospective cohort study

Characteristics

 

Naïve (n = 2,184)

Experienced (n = 2,672)

Total (n = 4,856)

%

p value

N

%

N

%

N

Socio-demographic

Gender

women

1,815

83.1

2,427

90.8

4,242

87.4

<0,001

men

369

16.9

245

9.2

614

12.6

Age

65–74

312

14.3

422

15.8

734

15.1

0.001

75–84

1,117

51.1

1,464

54.8

2,581

53.2

 ≥ 85

755

34.6

786

29.4

1,541

31.7

Severity

Previous fracture

Yes

285

13.1

627

23.5

912

18.8

<0,001

No

1,899

86.9

2,045

76.5

3,944

81.2

Charlson Index

0

899

41.2

1,149

43.0

2,048

42.2

0.357

1

631

28.9

766

28.7

1,397

28.8

>= 2

654

29.9

757

28.3

1,411

29.1

Health Services Use

Primary care visits

0–4

537

24.6

372

13.9

909

18.7

<0,001

5–12

810

37.1

910

34.1

1,720

35.4

13

837

38.3

1,390

52.0

2,227

45.9

ER visits

0

1,367

64

1,598

59.8

2,995

61.7

0.008

1

428

19.6

559

20.9

987

20.3

>= 2

359

16.4

515

19.3

874

18.0

Hospital visits

Yes

382

17.5

521

19.5

903

18.6

0.074

No

1,802

82.5

2,151

80.5

3,953

81.4

Polypharmacy

0–5

508

23.3

243

9.1

751

15.5

<0,001

6–12

1,256

57.5

1,539

57.6

2,795

57.6

≥13

420

19.2

890

33.3

1,310

27.0

Comorbidities

Osteoporosis

Yes

121

5.5

746

27.9

867

17.9

<0,001

No

2,063

94.5

1,926

72.1

3,989

82.2

Parkinson

Yes

94

4.3

136

5.1

230

4.7

0.200

No

2,090

95.7

2,536

94.9

4,626

95.3

Dementia

Yes

348

15.9

425

15.9

773

15.9

0.979

No

1,836

84.1

2,247

84.1

4,083

84.1

Diabetes

Yes

655

30

658

24.6

1,313

27.0

<0,001

No

1,529

70

2,014

75.4

3,543

73.0

Rheumatoid Artritis

Yes

51

2.3

95

3.6

146

3.0

0.013

No

2,133

97.7

2,577

96.4

4,710

97.0

Stroke

Yes

217

9.9

215

8.0

432

8.9

0.021

No

1,967

90.1

2,457

92.0

4,424

91.1

Myocardial infarction

Yes

199

9.1

236

8.8

435

9.0

0.735

No

1,985

90.9

2,436

91.2

4,421

91.0

Heart failure

Yes

164

7.5

183

6.9

347

7.2

0.374

No

2,020

92.5

2,489

93.1

4,509

92.9

Cancer

Yes

212

9.7

303

11.3

515

10.6

0.066

No

1,972

90.3

2,369

88.7

4,341

89.4

Medication

Osteoporosis–injectable

Yes

286

13.1

148

5.5

434

8.9

<0,001

No

1,898

86.9

2,524

94.5

4,422

91.1

Opioid treatment

Yes

421

19.3

918

34.4

1,339

27.6

<0,001

No

1,763

80.7

1,754

65.6

3,517

72.4

Sedative treatment

Yes

1,131

51.8

1,551

58.1

2,682

55.2

<0,001

No

1,053

48.2

1,121

41.9

2,174

44.8

SSRI treatment

Yes

421

19.3

705

26.4

1,126

23.2

<0,001

No

1,763

80.7

1,967

73.6

3,730

76.8

  1. ER: Emergency room; SSRI: Selective Serotonin Reuptake Inhibitors.