Figure 1 | Scientific Reports

Figure 1

From: Early X chromosome inactivation during human preimplantation development revealed by single-cell RNA-sequencing

Figure 1

Allelic expression during preimplantation development. Analyses of changes in fractions of biallelically and monoallelically expressed genes during development in male and female embryos. Fractions of biallelically (black) and monoallelically (red) expressed genes per total of expressed genes in each cell for each developmental stage are shown. (A) Dataset-1; (B) Dataset-2. Pearson’s r values (corr) are depicted in each panel. Non-paired Wilcoxon test was performed to compared the fractions of biallelically expressed X-linked genes between two stages in dataset-2. P-value (*) < 0.05; (***) ≤0.001; (ns) not significant. Numbers of genes analyzed and similar analysis of individual autosomes and are shown in Supplementary Fig. S3 and Supplementary Fig. S4, respectively.

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