Figure 4 | Scientific Reports

Figure 4

From: Gender-based differences in host behavior and gut microbiota composition in response to high fat diet and stress in a mouse model

Figure 4

Beta diversity analysis reveals that diet, gender, and stress significantly alter the composition of the gut microbiota. (a) Principle coordinate analysis (PCoA) based on Bray-Curtis dissimilarity of all OTUs from all the groups on Day 0, 81 and 136. (b) Clustering of gut microbiota based on distance between different groups calculated by MANOVA testing of the first 20 principal coordinates (accounting for 80% of total variation). (c) Comparison of the Bray-Curtis distance between NCD and HFD at each time point. (d) Comparison of the Bray-Curtis distance between females and males at each time point. All data is showed as mean ± SE For (c and d) the tests of significance were performed using a two-sided Student’s t-test with Bonferroni-correction, **P < 0.01 and *P < 0.05. N = 13–17 per group.

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