Figure 7 | Scientific Reports

Figure 7

From: Gender-based differences in host behavior and gut microbiota composition in response to high fat diet and stress in a mouse model

Figure 7

Co-abundance groups of the all the key OTUs in mice. (a) Network plot highlighting correlation relationships between 20 CAGs of prevalent OTUs (162 OTUs selected by Random Forest modeling). Node size indicates the average abundance (Hellinger tansformed) of the OTUs. Lines between nodes represent SparCC correlations between the nodes they connect, with line width indicating the correlation magnitude, and red and blue colors indicating positive and negative correlations, respectively. For clarity, only lines corresponding to correlations whose magnitude is greater than 0.4 were drawn, and unconnected nodes were omitted. (b) Heatmap of the false discovery rate (FDR) for CAGs, indicating the changes induced by sex, diet or stress. The tests of significance were performed using a two-sided Mann-Whitney test, and the calculation of FDR was performed using the procedure originally introduced by Benjamini and Hochberg33.

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