Figure 5 | Scientific Reports

Figure 5

From: 5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR

Figure 5

5-MTP upregulates FoxO3a and increases SOD and catalase activities. (A) FoxO3a proteins in LG-BM-MSCs and HG-BM-MSCs in the presence and absence of 5-MTP (10 μM) were analyzed by Western blotting. Upper panel shows representative blots and the lower panel, densitometric analysis of blots. Error bars denote mean ± SEM (n = 3). *p < 0.05. (B) SOD and (C) catalase activity in BM-MSCs incubated in LG or HG with or without 5-MTP. Error bars denote mean ± SEM (n = 3). *p < 0.05. **p < 0.01. N.S. non-significant.

Back to article page