Figure 1 | Scientific Reports

Figure 1

From: Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis

Figure 1

The expression of UPR genes and pro-fibrotic growth factors in granulosa-lutein cells from control (n = 10) and PCOS (n = 11) patients. The expression levels of (A–E) UPR genes, XBP1(S), HSPA5, ATF4, ATF6, and CHOP mRNA and (F,G) pro-fibrotic growth factors, TGF-β1 and CTGF mRNA in granulosa-lutein cells were measured by real-time PCR and normalized to that of GAPDH. Increased UPR gene expression was indicative of ER stress activation. The values represent means ± SEM. *p < 0.05.

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