Figure 4 | Scientific Reports

Figure 4

From: Cytoglobin Promotes Cardiac Progenitor Cell Survival against Oxidative Stress via the Upregulation of the NFκB/iNOS Signal Pathway and Nitric Oxide Production

Figure 4

Up-regulation of NFκB signal pathway following overexpressing CYGB. (a) Heat map of NFκB library screening by real time PCR array in response to CYGB overexpression. List of genes in this library was shown in the Supplemental Table S3. (b) Examination of NFκB gene expression at the mRNA level after CYGB was overexpressed. (c) Representative images and quantitative data of Western blot showing the expression of NFκB-associated proteins after CYGB was overexpressed. Full-length blots are presented in Supplemental Fig. S12. (d) LDH release assay after Bay117085 (5 µM) was applied to inhibit NFκB activity compared with vehicle controls. *Indicates p < 0.05 vs. control; **indicates p < 0.01 vs. control; n = 3 independent experiments.

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