Figure 9

Pathogenicity of the H7N9 NA stalk mutant viruses in mice. Viral replication in the nasal turbinate (A), trachea (B), and lung (C) and lung weights (D) of the infected mice (n = 5) were investigated with 106 PFU intranasal infection. The results were represented in average, and error bars denote SD (* P < 0.05 and *** P < 0.001 compared with the rH7N9 results).