Table 1 Pathological findings from the mice infected with the K/09 and ma viruses.

From: Adaptive mutations of neuraminidase stalk truncation and deglycosylation confer enhanced pathogenicity of influenza A viruses

Virus

MLD50

% of body weight lossa (dpi)

MDDb

MOCK

—

—

—

P0 (K/09)

 >106.5

11.79 ± 2.71 (6)

14.0 ± 0

ma-P1

105.5

15.38 ± 5.08 (7)

14.0 ± 0

ma-P3

104.1

22.03 (7)

7.6 ± 3.6

ma-P5

102.7

21.87 ± 1.74 (5)

5.4 ± 0.7

  1. aThe mean maximum body weight losses and bmean day of death (MDD) were obtained from the mice infected with 105 PFU. Each result was expressed in average with ± standard deviations (SD).