Table 3 Pathological findings from the mice infected with the K/09 and its NA stalk mutant viruses.

From: Adaptive mutations of neuraminidase stalk truncation and deglycosylation confer enhanced pathogenicity of influenza A viruses

Virus

MLD50

% of body weight lossa (dpi)

MDDb

MOCK

—

—

—

rK/09

 >106.5

12.70 ± 4.98 (6)

14.0 ± 0

rΔ53–60

103.9

24.45 ± 0.17 (6)

6.3 ± 0.48

rNN58SS

104.7

23.40 ± 1.32 (8)

9.5 ± 3.17

rN58T

105.1

18.90 ± 3.23 (7)

11.4 ± 3.57

  1. a,bPlease see footnotes in Table 1.
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