Figure 7
Predicted hydrophobic interactions between lonchocarpin and the BH3-binding groove of Bcl-2. (A) Hydrophobic surface represented in dark yellow color of lonchocarpin and Bcl-2 complex. (B) Hydrophobic interactions of lonchocarpin and Bcl-2 complex. The hydrophobic enclosure of Bcl-2 binding groove is represented by solid gray balls and the potential hydrophobic interaction of the ligand-protein complex is given by shot dashed yellow lines.
