Table 1 Effects of lonchocarpin on spleen index and tumor growth in S180-bearing mice (n = 8, mean ± SE) ***P < 0.001, compared to model groups.

From: A natural chalcone induces apoptosis in lung cancer cells: 3D-QSAR, docking and an in vivo/vitro assay

Group

Dose[mg/kg]

Mouse number

Body weight/g

Tumor weight/g

Inhibitory rate (%)

Spleen index (mg/g)

After experiment

Before experiment

Model

0

8

27.43 ± 0.30

37.22 ± 0.48

8.05 ± 1.15

0

3.72

Lonchocarpin

25

8

26.45 ± 0.68

39.19 ± 2.15

3.39 ± 0.69***

57.94

3.08

50

8

28.99 ± 0.47

36.48 ± 1.38

2.95 ± 0.66***

63.40

3.17

100

8

28.21 ± 1.98

38.71 ± 2.20

2.21 ± 0.72***

72.51

3.30

CTX

25

8

28.09 ± 0.56

35.97 ± 0.89

1.55 ± 0.30***

80.75

4.77

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