Figure 3

IL-37 suppresses the expression of pro-inflammatory cytokines in PBMCs from EIOA patients. The mRNAs expression of TNF-α (a), IL-1β(b) and IL-6 (c) in PBMCs from EIOA patients (n = 32) and HCs (n = 40) were analyzed by RT-PCR, the supernatants produced by PBMCs were collected for measuring TNF-α(d), IL-1β (e) and IL-6 (f) protein levels by ELISA.