Figure 5
Multivariate data analyses of plasma based on UPLC-Q-TOF/MS analysis. (a,b) PCA score plot based on the plasma metabolic profiling of the control and atherosclerosis hamsters in positive and negative modes, ESI+: R2 = 0.627, ESI−: R2 = 0.625. (c,d) PLS-DA score plots of the control, HFD and AEE groups, ESI+: R2X = 0.424, R2Y = 0.911, Q2 = 0.813; ESI−: R2X = 0.613, R2Y = 0.917, Q2 = 0.829. (e,f) Permutation test of the PLS-DA models, ESI+: the intercepts of R2 = 0.468 and Q2 = −0.373, ESI−: R2 = 0.50, Q2 = −0.508.
