Figure 8 | Scientific Reports

Figure 8

From: Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression

Figure 8

Summary of the key results (a), and schematic diagram depicting the epigenetic mechanism of Arg-induced HIF-1α degradation at the ASS1 promoter as described in the text (b). HIF-1α usually complexes with one β member of the HIF the family (HIF-1β, HIF-2β, and HIF-3β) which is constitutively expressed. For simplicity, we only show HIF-1α at the ASS1 promoter here.

Back to article page