Table 5 Clinicopathological features of patients with concomitant EGFR and ALK alterations.

From: Homogeneity and High Concordance of ALK Translocation in Primary Lung Adenocarcinoma and Paired Lymph Node Metastasis

Features

P1

P2

P3

P4

P5

Age

70

64

43

51

64

Sex

F

M

M

M

F

Smoking

no

yes

yes

no

no

Stage

IA

IIIA

IA

IIIA

IA

EGFR mutation

E19 del (2235–2249)

E19 del (2240–2257)

E19 del (2235–2257)

E21L858R

E21L858R

ALK Ventana IHC

+

+

+

+

+

KRAS

WT

WT

WT

WT

WT

BRAF

WT

WT

WT

WT

WT

HER-2

WT

WT

WT

WT

WT

  1. Abbreviation: P, patient; F, female; M, man; Del, deletion; IHC, immunohistochemistry; WT, wild-type.