Figure 5 | Scientific Reports

Figure 5

From: IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways

Figure 5

Allergen-specific memory CD4 T cells residing in the lung and airways induced eosinophilic inflammation. (a) Mice were challenged and treated with FTY720 on days 21, 22, 24, and 26 post challenge. Mice were rechallenged with PBS or a mixture of HDM and OVA on day 24 and 25, and then sacrificed on day 27. (b) The number of OVA-specific CD4 T cells was counted. Bar graph depicts Mean ± SEM. (c) Total cell numbers were counted using trypan blue staining. Eosinophil numbers were counted by cytospin and Diff-Quick staining. Bar graph depicts Mean ± SEM (***P < 0.001; ns: not significant). Similar experiments were repeated three times. Eight mice for each group were used and three experimental data sets were compiled.

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