Figure 6

ArsC enzyme from E. coli. (A) Overview of ArsC from E. coli bound to arsenate (represented as sticks in purple and red) and sulfate (yellow and red). (B) Three most conserved positions in ArsC homologs. (C–F) The four sets of coevolved positions among ArsC homologs. Asterisks refer to positions that show an alternative residue in ArsC from E. coli.