Figure 6
Effect of transmural and axial pressure differences (N = 5). (A) Representative pressure vs. diameter in a single contraction cycle without R capillary (black) and with R capillary upstream (magenta) for p in = p out = 3, 5, 7 cmH2O (left to right). Passive pressure-diameter curve is in green. (B) Top: without R capillary. Average Suction amp at p in = p out = 3, 5, 7 cmH2O (N = 5, p e = 0.5 cmH2O) (left). †Significant difference from 0 (p < 0.01). Relative increase in Suction amp at p in = p out = 5, 7 cmH2O relative to p in = p out = 3 cmH2O averaged for five vessels (right). *Significant difference from 1 (p < 0.01). Bottom: same plots with R capillary upstream. (C) Relative increase in Suction amp at p in = p out = 3, 5, 7 cmH2O following deployment of R capillary and averaged for five vessels. †Significant difference from 0 (p < 0.01). (D) Representative pressure vs. diameter in a single contraction cycle without R capillary (black) and with R capillary upstream (magenta) for p in, p out = (3, 7), (5, 5), (7, 3) cmH2O (left to right). (E) Top: without R capillary. Average Suction amp at p in, p out = (3, 7), (5, 5), (7, 3) cmH2O (N = 5, p e = 0.5 cmH2O) (left). †Significant difference from 0 (p < 0.01). Fold change in Suction amp at p in, p out = (7, 3), (3, 7) cmH2O relative to p in = p out = 5 averaged for five vessels (right). †Significant difference from 0 (p < 0.01). Bottom: same plots with R capillary upstream. (F) Fold increase in Suction amp at p in, p out = (3, 7), (5, 5), (7, 3) cmH2O following deployment of R capillary averaged for five vessels. Error bars indicate standard deviation. *Significant difference from 1 (t-test, p < 0.01).
