Figure 8

Stepwise processing of Vip3Ab1. For simplicity, numbering is based on the sequence numbering of full length Vip3Ab1. An initial cleavage site Arg¹²↓Ala¹³ removes the N-terminal 12 amino acids from Vip3Ab1. This is followed by a second processing site at Lys¹⁹⁹↓Asp²⁰⁰ to produce ~20 kDa and 65 kDa fragments.