Figure 4
From: MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity
Box plots and ROC curves for miR-122-5p, miR-378a-5p, miR-125b-5p and miR-27b-3p. (A) Depicts box plots of circulating miRNAs in serum from healthy and APAP overdose samples. Data was normalized for miRNA expression with let-7d and spiked C. elegans miR-39. Data were presented as a box plot of the median and range of log transformed relative expression level. The top and bottom of the box represent the 75th and 25th percentile. (B) Shows receiver operating characteristics (ROC) curve analysis, indicating diagnostic value of each miRNA in discriminating APAP toxicity.
