Table 4 Risk factors for CLI in diabetes by binary logistic regression analysis.

From: Siglec-5 is a novel marker of critical limb ischemia in patients with diabetes

 

OR

95% CI for OR

P

OR*

95% CI for OR*

P *

Sex

0.494

0.258–0.946

0.033

Age

1.160

1.110–1.214

0.000

T2D Duration

1.163

1.098–1.231

0.000

SBP

1.041

1.023–1.061

0.000

TC

0.652

0.466–0.913

0.013

Apo A

0.061

0.011–0.333

0.001

Cr

1.024

1.008–1.039

0.002

BUN

1.319

1.103–1.577

0.002

Total bilirubin

0.867

0.807–0.931

0.000

Trappin-2

1.065

1.035–1.095

0.000

0.987

0.933–1.043

0.637

IGFBP-6

1.005

1.001–1.008

0.005

0.993

0.984–1.002

0.117

BMP-4

1.001

1.000–1.003

0.039

1.001

0.997–1.004

0.709

Decorin

1.000

1.000–1.001

0.005

1.000

0.999–1.001

0.744

Siglec-5

1.043

1.029–1.057

0.000

1.077

1.028–1.128

0.002

TIMP-4

1.000

1.000–1.001

0.003

0.994

0.000–3066.573

0.999

CDH5

1.106

1.050–1.166

0.000

1.205

1.003–1.449

0.057

  1. CI, confidence interval. Logistic regression models were used to calculate OR. *Adjusted for sex, age, T2D Duration, SBP, TC, Apo A, Cr, BUN, Total bilirubin. pg/ml (Trappin-2, IGFBP-6, BMP-4), ng/ml (Decorin, Siglec-5, TIMP-4). All study subjects were included in the analysis. Significant values are marked in italic.