Table 1 Characteristics of patients with pre-CCRT specimens.
Patient characteristic | Total (%) (Nā=ā45) |
---|---|
Age (years) | |
Ā Mean (SD) | 63.9 (9.8) |
Sex | |
Ā male | 36 (80) |
Smoking status | |
Ā never-smoker | 6 (13) |
Ā current or former smoker | 39 (87) |
Histology | |
Ā adenocarcinoma | 19 (42) |
Ā squamous | 24 (53) |
Ā others | 2 (5) |
Stage | |
Ā II A | 6 (13) |
Ā II B | 8 (18) |
Ā III A | 30 (67) |
Ā III B | 1 (2) |
ECOG-PS | |
Ā 0 | 26 (58) |
Ā 1 | 19 (42) |
Chemo-radiotherapy regimen | |
Ā Vinorelbine plus platinum | 30 (67) |
Ā Docetaxel plus platinum | 10 (23) |
Ā Paclitaxel plus platinum | 3 (6) |
Ā S1 plus platinum | 1 (2) |
Ā Pemetrexed plus platinum | 1 (2) |
Radiotherapy dose | |
Ā 40āGy | 38 (84) |
Ā 50āGy | 7 (16) |
Down staging * | |
Ā Yes | 32 (71) |
Ā No | 13 (29) |
PD-L1 status on tumor cells before CCRT | |
Ā positive | 28 (62) |
Ā negative | 17 (38) |
CD8+ lymphocytes density before CCRT** | |
Ā high | 0 (0) |
Ā intermediate | 14 (33) |
Ā low | 29 (67) |