Table 1 Characteristics of patients with pre-CCRT specimens.

From: Alteration of PD-L1 expression and its prognostic impact after concurrent chemoradiation therapy in non-small cell lung cancer patients

Patient characteristic

Total (%) (N = 45)

Age (years)

Ā Mean (SD)

63.9 (9.8)

Sex

Ā male

36 (80)

Smoking status

Ā never-smoker

6 (13)

Ā current or former smoker

39 (87)

Histology

Ā adenocarcinoma

19 (42)

Ā squamous

24 (53)

Ā others

2 (5)

Stage

Ā II A

6 (13)

Ā II B

8 (18)

Ā III A

30 (67)

Ā III B

1 (2)

ECOG-PS

Ā 0

26 (58)

Ā 1

19 (42)

Chemo-radiotherapy regimen

Ā Vinorelbine plus platinum

30 (67)

Ā Docetaxel plus platinum

10 (23)

Ā Paclitaxel plus platinum

3 (6)

Ā S1 plus platinum

1 (2)

Ā Pemetrexed plus platinum

1 (2)

Radiotherapy dose

Ā 40 Gy

38 (84)

Ā 50 Gy

7 (16)

Down staging *

Ā Yes

32 (71)

Ā No

13 (29)

PD-L1 status on tumor cells before CCRT

Ā positive

28 (62)

Ā negative

17 (38)

CD8+ lymphocytes density before CCRT**

Ā high

0 (0)

Ā intermediate

14 (33)

Ā low

29 (67)

  1. SD, standard deviation; ECOG PS, Eastern Cooperative Oncology Group Performance Status; PD-L1, programmed cell death ligand-1; CCRT, concurrent chemo-radiation therapy.
  2. *Pathological stage compared with clinical stage.
  3. **We had sufficient material with stroma and tumor cells before CCRT in 43 patients.