Table 2 Associations between baseline serum biomarkers levels (in quartiles) and GC risk.
From: Three-dimensional combined biomarkers assay could improve diagnostic accuracy for gastric cancer
Serum biomarkers | GC vs. control | |||
|---|---|---|---|---|
GC (n) | Con (n) | OR (95% CI) | P a value | |
PGI (ng/mL) | ||||
Quartile 1(0–64.1) | 119 | 84 | 5.12(1.81,14.45) | 0.002 |
Quartile 2(64.2–84.0) | 65 | 82 | 1.60(0.53,4.84) | 0.409 |
Quartile 3 (84.1–118.0) | 56 | 84 | 0.86(0.26,2.88) | 0.806 |
Quartile 4 (118.1–744.9) | 91 | 82 | Reference | N/A |
PGII (ng/mL) | ||||
Quartile 1(0–5.4) | 64 | 86 | Reference | N/A |
Quartile 2(5.5–7.3) | 36 | 84 | 0.58(0.35,0.96) | 0.033 |
Quartile 3 (7.4–11.0) | 50 | 80 | 0.84(0.52,1.36) | 0.475 |
Quartile 4 (11.1–198.1) | 181 | 82 | 2.97(1.96,4.49) | 0.000 |
PGI/II | ||||
Quartile 1(0–8.5) | 216 | 83 | 9.17(5.41,15.54) | 0.000 |
Quartile 2(8.6–11.6) | 52 | 85 | 2.15(1.21,3.84) | 0.009 |
Quartile 3 (11.7–15.8) | 41 | 83 | 1.74(0.96,3.16) | 0.068 |
Quartile 4 (15.9–42.0) | 23 | 81 | Reference | N/A |
HpAb (EIU) | ||||
Quartile 1(−0.6–4.3) | 25 | 84 | Reference | N/A |
Quartile 2(4.4–12.1) | 47 | 83 | 1.90(1.07,3.37) | 0.216 |
Quartile 3 (12.2–28.1) | 74 | 83 | 3.00(1.74,5.17) | 0.000 |
Quartile 4 (28.2–180.3) | 186 | 82 | 7.62(4.55,12.78) | 0.000 |
OPN (ng/mL) | ||||
Quartile 1(0–0.9) | 31 | 87 | Reference | N/A |
Quartile 2(1.0–1.6) | 41 | 81 | 1.42(0.81,2.48) | 0.028 |
Quartile 3 (1.7–3.0) | 82 | 84 | 2.74(1.64,4.56) | 0.000 |
Quartile 4 (3.1–26.4) | 178 | 80 | 6.24(3.83,10.17) | 0.000 |
