Table 4 Accuracy of OPN, PGI/II, HpAb individually and combined for GC detection.
From: Three-dimensional combined biomarkers assay could improve diagnostic accuracy for gastric cancer
Biomarker | cutoff | Sensitivity (%) | Specificity (%) | LR+ | LR− | Accuracy (%) | YD |
---|---|---|---|---|---|---|---|
PGI/II | 7.0 | 54.2 | 81.0 | 2.9 | 0.7 | 56.5 | 0.352 |
HpAb (EIU) | 34.0 | 51.5 | 81.0 | 2.7 | 0.6 | 66.3 | 0.325 |
OPN (ng/ml) | 2.6 | 64.2 | 67.5 | 2.0 | 0.7 | 53.1 | 0.316 |
PGI/II- HpAb | 0.472a | 70.5 | 75.3 | 2.9 | 0.4 | 72.9 | 0.458 |
OPN- HpAb | 0.462a | 70.2 | 76.8 | 3.0 | 0.4 | 73.5 | 0.470 |
PGI/II-OPN | 0.495a | 71.1 | 73.5 | 2.7 | 0.4 | 72.3 | 0.446 |
PGI/II-OPN-HpAb | 0.493a | 70.2 | 78.3 | 3.2 | 0.4 | 74.3 | 0.485 |